Implication of Ccr4-Not complex function in mRNA quality control in Saccharomyces cerevisiae

Jannie Assenholt1, John Mouaikel, Cyril Saguez

  • 1Department of Molecular Biology, Aarhus University, Aarhus C., Denmark.

RNA (New York, N.Y.)
|August 25, 2011
PubMed
Summary

The Ccr4-Not complex links to nuclear messenger ribonucleoprotein particle (mRNP) quality control (QC) in yeast. Deleting Ccr4-Not components rescues defects caused by mutations in the THO complex, suggesting a role in nuclear mRNP QC.

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