Altered Endoplasmic Reticulum Calcium Pump Expression during Breast Tumorigenesis

Béla Papp1, Jean-Philippe Brouland

  • 1Institut National de la Santé et de la Recherche Médicale, Inserm UMR-S 940, Institut Universitaire d'Hématologie, 16, rue de la Grange aux Belles, 75010 Paris, Université Paris Diderot, Sorbonne Paris Cité

Summary

The study found that Sarco/Endoplasmic Reticulum Calcium ATPase 3 (SERCA3) expression decreases in early breast lesions and correlates with tumor malignancy. This suggests altered endoplasmic reticulum calcium homeostasis during breast tumorigenesis.

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