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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

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Updated: May 30, 2026

Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
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Brain SPECT Imaging in Complex Psychiatric Cases: An Evidence-Based, Underutilized Tool.

Daniel G Amen1, Manuel Trujillo, Andrew Newberg

  • 1Amen Clinics, Inc.

The Open Neuroimaging Journal
|August 25, 2011
PubMed
Summary

Brain Single Photon Emission Computed Tomography (SPECT) imaging is evidence-based and recommended for psychiatric practice. This article advocates for its wider clinical use in complex cases, detailing seven applications to improve patient care.

Keywords:
Brain SPECTbrain traumacomplex cases.dementiaevidence basedtoxicity

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Area of Science:

  • Neuroimaging
  • Nuclear Medicine
  • Psychiatric Diagnostics

Background:

  • Brain Single Photon Emission Computed Tomography (SPECT) imaging has a robust evidence base over 20 years.
  • Professional societies recommend SPECT for various psychiatric indications.
  • Current clinical utilization of SPECT in psychiatry is limited.

Purpose of the Study:

  • To present a rationale for increased clinical use of brain SPECT.
  • To highlight SPECT's utility in managing complex psychiatric cases.
  • To outline seven specific clinical applications of SPECT in patient care.

Main Methods:

  • Review of evidence supporting brain SPECT in psychiatric practice.
  • Identification of clinical scenarios where SPECT can optimize care.
  • Development of a framework for integrating SPECT into routine practice.

Main Results:

  • Brain SPECT is supported by substantial evidence for psychiatric indications.
  • Limited adoption hinders the potential benefits of SPECT.
  • Seven distinct clinical applications are proposed for optimizing patient management.

Conclusions:

  • Widespread adoption of brain SPECT can enhance psychiatric practice.
  • SPECT offers valuable insights for complex psychiatric cases.
  • Further integration of SPECT is recommended to improve patient outcomes.