[Impact of iatrogenic preterm birth on newborn morbidity]

Area of Science:

• Obstetrics and Gynecology
• Neonatal Medicine
• Public Health

Background:

• The incidence of premature births is increasing in developed nations.
• This rise is largely attributed to iatrogenic late preterm births (34 weeks + 0 days to 36 weeks + 6 days gestation).
• Late preterm births constitute up to 80% of all preterm deliveries and are associated with increased neonatal morbidity, mortality, and long-term neurodevelopmental impairments compared to term infants.

Purpose of the Study:

• To highlight the increasing trend of late preterm births.
• To emphasize the associated adverse outcomes in newborns.
• To advocate for the implementation of standardized treatment protocols to mitigate iatrogenic preterm births.

Main Methods:

• Analysis of trends in preterm birth incidence.
• Review of neonatal outcomes associated with late preterm births.
• Identification of key clinical conditions contributing to iatrogenic preterm birth.

Main Results:

• A discernible increase in the overall incidence of premature births.
• Late preterm births are a significant contributor, accounting for a substantial majority of preterm deliveries.
• Newborns born late preterm exhibit elevated risks for mortality and neurodevelopmental issues.

Conclusions:

• There is an urgent need to address the rising rates of iatrogenic late preterm births.
• Standardized treatment algorithms are crucial for managing conditions such as mild preeclampsia and intrauterine growth restriction.
• Implementing evidence-based protocols can help reduce the incidence of preventable preterm births and improve neonatal outcomes.