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Published on: August 21, 2017
Antiphospholipid syndrome following toxoplasma retinochoroiditis
Mehdi Tavakoli1, Shiva Roghaee, Roham Soheilian
1Ophthalmology Department and Ophthalmic Research Center, Labbafinejad Medical Center, Shahid Beheshti Medical University, Tehran, Iran.
Purpose:
To report a case of antiphospholipid syndrome (APS) following toxoplasma retinochoroiditis.
Design:
Interventional case report.
Method:
The patient was a 24-year-old female with an attack of visual loss due to toxoplasma retinochoroiditis concomitant with branch retinal vein occlusion. Retinitis resolved with anti-toxoplasma treatment. However, a recurrent episode of BRVO and vitreous hemorrhage occurred later.
Result:
In systemic evaluation, evidence of APS was detected, including high titers of anti-cardiolipin antibody, increased beta-2 microglobulin and anti-toxoplasma IgG antibody, and also low titers of C3, C4, and CH50.
Conclusion:
Ocular toxoplasmosis should be included in the list of etiologies of secondary APS. Systemic evaluation for detection of APS is a necessary approach to patients with toxoplasma retinochoroiditis and concomitant vascular accident.
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