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Updated: May 30, 2026

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Published on: May 10, 2024
Pathology of oesophagitis
Aoife Maguire1, Kieran Sheahan
1Department of Histopathology, St Vincent's University Hospital, Dublin, Ireland.
Oesophagitis, or oesophageal inflammation, has overlapping histopathological features. This review aids pathologists by correlating endoscopic images with microscopic findings for accurate diagnosis.
Area of Science:
- Gastroenterology
- Pathology
- Endoscopy
Background:
- Oesophagitis is common worldwide, characterized by oesophageal mucosa inflammation and damage.
- Diverse etiological agents (physical, chemical, infectious) cause oesophagitis.
- Histopathological features often overlap due to the oesophagus's limited response to injury.
Purpose of the Study:
- To present clinicopathological descriptions of major oesophagitis types.
- To highlight the importance of correlating clinical, endoscopic, and microscopic findings.
- To enhance diagnostic accuracy in oesophagitis cases.
Main Methods:
- Review of clinicopathological descriptions of major oesophagitis types.
- Emphasis on the role of endoscopic macroscopic descriptions and images.
- Integration of microscopic findings with clinical and endoscopic data.
Main Results:
- Oesophagitis diagnosis relies on integrating multiple data sources.
- Endoscopic visualization significantly aids pathological interpretation.
- Understanding clinicopathological correlations is key to differentiating oesophagitis types.
Conclusions:
- Accurate oesophagitis diagnosis requires a multidisciplinary approach.
- Pathologists benefit from endoscopic imaging and clinical information.
- This review provides a framework for diagnosing common oesophagitis presentations.
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