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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
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Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

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Tree Core Analysis with X-ray Computed Tomography
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Toward quantitative core-loss EFTEM tomography.

N Y Jin-Phillipp1, C T Koch, P A van Aken

  • 1Stuttgart Center for Electron Microscopy, Max-Planck-Institut für Metallforschung, Heisenbergstr. 3, 70569 Stuttgart, Germany. nyjin@mf.mpg.de

Ultramicroscopy
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Energy-filtered transmission electron microscopy (EFTEM) tomography offers 3D chemical mapping. A new correction method improves 3D elemental distribution accuracy in thicker samples, overcoming scattering limitations.

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Area of Science:

  • Materials Science
  • Microscopy
  • Nanotechnology

Background:

  • Core-loss EFTEM tomography is a powerful technique for 3D structural and chemical analysis.
  • Applications are often limited by multiple scattering in thick specimens and diffraction contrast.

Purpose of the Study:

  • To demonstrate the capability of core-loss EFTEM tomography for thin layer reconstruction.
  • To develop and validate a multiple-scattering correction method for thicker samples.
  • To discuss experimental parameters influencing EFTEM 3D elemental mapping accuracy.

Main Methods:

  • Demonstrated core-loss EFTEM tomography on a few-monolayer carbon layer over Fe catalyst.
  • Proposed and applied an approximate multiple-scattering correction using zero-loss images.
  • Tested the method on copper whiskers to assess 3D elemental distribution.

Main Results:

  • Successfully reconstructed a thin carbon layer on an Fe catalyst.
  • The multiple-scattering correction significantly improved 3D elemental distribution in copper whiskers.
  • The method enhances the accuracy of EFTEM 3D elemental mapping.

Conclusions:

  • Core-loss EFTEM tomography is viable for thin layer analysis.
  • The proposed correction method effectively mitigates scattering artifacts in thicker samples.
  • Optimizing experimental parameters is crucial for accurate 3D elemental mapping with EFTEM.