Glandular odontogenic cyst: two high-risk cases treated with conservative approaches

The glandular odontogenic cyst is a rare jawbone cyst that is considered to be an independent entity, although its histopathological characteristics may lead to an incorrect diagnosis as a low-grade mucoepidermoid carcinoma. The treatment of glandular odontogenic cysts is controversial.

We present two high-risk cases treated with conservative approaches, one by enucleation and curettage and the other by marsupialisation. This report also presents a review of the clinical and pathological aspects of glandular odontogenic cysts, and considers their development. No evidence of disease was observed after 3 years of follow-up in the two cases presented.

When possible, treatment plans for these lesions should be customised for each case, taking into account the data available in the literature and patient preferences. For high-risk cases, that are treated with conservative approaches, such as the two cases presented here, strict and regular controls and rigorous radiological follow-up evaluations are mandatory.