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Related Concept Videos

Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Cells of the Epidermis01:24

Cells of the Epidermis

The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: May 29, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
03:47

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Ablative skin resurfacing.

Jennifer Chwalek, David J Goldberg

    Current Problems in Dermatology
    |August 26, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Ablative skin resurfacing, using CO(2) and Er:YAG lasers, effectively treats photodamage and acne scars. Newer laser technologies offer improved results with fewer side effects and faster recovery.

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    Area of Science:

    • Dermatology
    • Laser Technology
    • Aesthetic Medicine

    Background:

    • Ablative skin resurfacing is a gold standard treatment for photodamage and acne scars.
    • Early CO(2) lasers caused significant thermal damage, leading to high complication rates.
    • Advancements in laser technology have led to safer and more effective resurfacing.

    Purpose of the Study:

    • To review the background of ablative lasers.
    • To discuss the mechanism of action, indications, and side effects of ablative resurfacing.

    Main Methods:

    • Review of ablative laser technology.
    • Discussion of laser-tissue interaction.
    • Analysis of clinical outcomes and patient selection.

    Main Results:

    • CO(2) and Er:YAG lasers target water, inducing collagen formation and tissue contraction.
    • Modern ablative lasers, including fractional and pulsed devices, provide significant improvements with reduced side effects.
    • Careful patient selection is crucial to minimize risks like scarring, dyspigmentation, and infection.

    Conclusions:

    • Ablative skin resurfacing has evolved significantly, offering safer and more effective treatment options.
    • Understanding laser mechanisms and potential side effects is key for successful patient outcomes.
    • Continued advancements aim to further enhance safety and efficacy in skin resurfacing procedures.