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Related Concept Videos

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Mitochondria01:37

Mitochondria

Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Replicative Cell Senescence02:15

Replicative Cell Senescence

Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds the telomeric...
Replicative Cell Senescence02:15

Replicative Cell Senescence

Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds the telomeric...

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Related Experiment Video

Updated: May 29, 2026

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
13:59

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence

Published on: August 12, 2018

Photoaging.

Lisa Danielle Grunebaum, Ryan N Heffelfinger

    Current Problems in Dermatology
    |August 26, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Fractional laser resurfacing effectively treats photoaging signs like wrinkles and pigmentation. Both ablative and non-ablative lasers offer safe and effective results when used by experienced practitioners.

    Related Experiment Videos

    Last Updated: May 29, 2026

    A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
    13:59

    A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence

    Published on: August 12, 2018

    Area of Science:

    • Dermatology
    • Cosmetic Surgery
    • Laser Medicine

    Background:

    • Photoaging, characterized by wrinkles, pigmentation, and texture changes, is a common cosmetic concern.
    • Traditional laser resurfacing treatments have been used to address these signs of aging.

    Purpose of the Study:

    • To review the effectiveness and safety of modern laser resurfacing techniques for photoaging.
    • To highlight advancements in fractional laser technology.

    Main Methods:

    • Review of current literature on ablative and non-ablative fractional laser resurfacing.
    • Analysis of treatment outcomes for photoaging concerns.

    Main Results:

    • Fractional laser resurfacing, utilizing both ablative and non-ablative wavelengths, demonstrates efficacy in treating fine rhytides, dyspigmentation, and abnormal skin texture.
    • Recent advancements have enhanced the safety profile and reduced side effects associated with laser resurfacing.

    Conclusions:

    • Both ablative and non-ablative fractional laser wavelengths are effective treatment options for photoaging.
    • Experienced practitioners are crucial to minimize risks such as scarring and pigment alterations.