Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A low flow open circle system for anaesthesia. Part 2: Clinical evaluation.

A Holdcroft1, M K Chakrabarti, J G Whitwam

  • 1Department of Anaesthetics, Royal Postgraduate Medical School, London.

Anaesthesia
|April 1, 1990
PubMed
Summary

A novel valveless ventilator system using low-flow anesthetic gases proved safe and versatile for patient ventilation during surgery. This open circle system maintained stable oxygen and nitrous oxide levels, offering advantages over existing methods.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heat killed multi-serotype Shigella immunogens induced humoral immunity and protection against heterologous challenge in rabbit model.

Immunobiology·2015
Same author

Ecology ofVibrio cholerae in the freshwater environs of Calcutta, India.

Microbial ecology·2013
Same author

Cannabinoids and pain relief.

Expert review of neurotherapeutics·2009
Same author

Factors in the choice of oral transmucosal fentanyl citrate dose for adult burns dressings.

Burns : journal of the International Society for Burn Injuries·2009
Same author

Is preparation for emergency obstetric anaesthesia adequate? A maternal questionnaire survey.

International journal of obstetric anesthesia·2007
Same author

Analgesia with sevoflurane during labour: i. Determination of the optimum concentration.

British journal of anaesthesia·2006

Area of Science:

  • Anesthesiology
  • Respiratory Care
  • Medical Device Engineering

Background:

  • Traditional anesthesia delivery systems can be complex and resource-intensive.
  • Low-flow anesthesia techniques aim to reduce gas consumption and waste.
  • The need for adaptable and safe ventilation methods in surgical settings is critical.

Purpose of the Study:

  • To evaluate a prototype valveless ventilator integrated with an open circle system.
  • To assess the safety and efficacy of low-flow anesthetic gas delivery during surgery.
  • To compare the performance of this novel system against existing ventilation methods.

Main Methods:

  • A prototype valveless ventilator was connected to an open deadspace tubing circle system.
  • Twelve patients undergoing intra-abdominal surgery were ventilated for 60-120 minutes.

Related Experiment Videos

  • Anesthetic gases (nitrous oxide 50% in oxygen and enflurane) were delivered at low flows (2 L/min) after stabilization.
  • Main Results:

    • The system successfully ventilated patients during surgery.
    • Measured inspired oxygen and nitrous oxide concentrations remained stable throughout the low-flow period.
    • No significant variations in key anesthetic gas concentrations were observed.

    Conclusions:

    • The prototype valveless ventilator with an open circle system demonstrates safety and versatility.
    • This low-flow anesthesia system offers potential advantages over conventional methods.
    • Further research is warranted to explore its broader clinical applications.