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Updated: May 29, 2026

Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases
Published on: March 1, 2024
["Common variable immunodeficiency"--first diagnosis of a rare pneumological disease]
C Priegnitz1, K Berg, W Galetke
1Institut für Pneumologie an der Universität Witten Herdecke, Krankenhaus Bethanien gGmbH, Aufderhöher Strasse 169-175, Solingen. christina.priegnitz@klinikbethanien.de
Abstract:
Common variable immunodeficiency (CVID) is generally used synonymously with "late onset hypogammaglobulinaemia", which is already indicative of the central pathological finding. Patients with CVID produce specifically less immunoglobulins, thus reducing their immunological competence. Our patient showed the typical medical history of undetected CVID. After excluding differential pneumological diseases, the suspected diagnosis was confirmed. This case report examines the complex of CVID as a cause for recurrent pneumological infections. It is the most prevalent form of severe antibody deficiency in children and adults and occurs with a probability of 1:25,000 in the population.
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