[Correlation between Chinese medicine syndrome types of polycystic ovary syndrome and ovulation induction effect]

To study the correlation between Chinese medicine syndrome types of polycystic ovary syndrome (PCOS) and ovulation induction effect, and its clinical significance.

Eighty patients with clinically confirmed PCOS were syndrome differentiated as four types, i.e., Shen-yin deficiency syndrome (21 cases), Shen-yang deficiency syndrome (18 cases), phlegm-dampness accumulation syndrome (19 cases), and Gan-stagnancy transformed heat syndrome (22 cases). They all took 100 mg clomiphene as the ovulation induction for 5 successive days. Results of ovulation in all patients were analyzed and compared.

Ovulation induction and the conception rate were sequenced from high to low as follows: Shen-yang deficiency syndrome (66.7%, 22.2%), Gan-stagnancy transformed heat syndrome (59.1%, 18.2%), Shen-yin deficiency syndrome (28.6%, 9.5%), and phlegm-dampness accumulation syndrome (26.3%, 5.3%). Significant difference was shown in ovulation induction results when compared Shen-yang deficiency syndrome with Shen-yin deficiency syndrome and phlegm-dampness accumulation syndrome (P<0.05) as well as when compared Ganstagnancy transformed heat syndrome with Shen-yin deficiency syndrome and phlegm-dampness accumulation syndrome (P<0.05). Significant difference was shown in the conception rate between Shen-yang deficiency syndrome and phlegm-dampness accumulation syndrome (P<0.05).

The effects of ovulation induction in patients of phlegm-dampness accumulation syndrome and of Shen-yin deficiency syndrome were poorer than those in patients of Shen-yang deficiency syndrome and Gan-stagnancy transformed heat syndrome, which indicated the reproduction endocrine abnormality or the metabolism abnormality degree of the former two syndrome types were more server than the latter two syndrome types.