Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
Lipid Catabolism01:25

Lipid Catabolism

Triglycerides serve as crucial long-term energy storage molecules in microorganisms, providing a dense source of metabolic energy. Their breakdown is mediated by lipases, which hydrolyze triglycerides into glycerol and free fatty acids. Each of these components follows distinct metabolic pathways, ultimately contributing to ATP synthesis and cellular energy homeostasis.Glycerol MetabolismGlycerol, released from triglyceride hydrolysis, is phosphorylated by glycerol kinase to form...
Fischer Projections02:18

Fischer Projections

Learning to draw Fischer projections of molecules and understanding their relevance plays a crucial role in the visual depiction of organic molecules. A Fischer projection is a two-dimensional projection on a planar surface to simplify the three-dimensional wedge–dash representation of molecules. This is especially helpful in the case of molecules with multiple chiral centers that can be difficult to draw. Here, all the bonds of interest are represented as horizontal or vertical lines. While...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Morning priming exercises for explosive performance: time course effects of two-way ballistic and strength-based protocols.

Biology of sport·2026
Same author

Blood Flow Restriction Does Not Impair Single, All-Out Sprint Cycling Performance.

European journal of sport science·2026
Same author

Live high, train smart: translating altitude physiology to best practice with mechanistic insights.

Frontiers in physiology·2026
Same author

Effects of caffeine intake on exercise performance in basketball players: a systematic review and meta-analysis.

Frontiers in nutrition·2026
Same author

Comparative Precision of 3D MRE and 2D MRE for Measurement of Liver Stiffness in Adults with Severe Obesity.

Radiology·2026
Same author

Energy Expenditure Analysis and Prediction in Smith Machine Squats Integrating Mechanical Loads and Sex.

Journal of strength and conditioning research·2026
Same journal

Incremental diagnostic value of microstructural time-dependent diffusion MRI in differentiating PCNSL from glioblastoma over conventional MRI.

Magnetic resonance imaging·2026
Same journal

Enhanced motion compensation for free-breathing dynamic contrast-enhanced MRI with GROG-facilitated bunch phase encoding and Golden angle radial sampling.

Magnetic resonance imaging·2026
Same journal

The allegory of the cave: 10 years of AI shadows in radiology.

Magnetic resonance imaging·2026
Same journal

Conversion of 3 T liver, spleen, pancreas, and kidney R2* measurements to 1.5 T R2* equivalents: Validation of a theoretical framework.

Magnetic resonance imaging·2026
Same journal

Cine-derived mitral annular relaxation velocity for detection of preclinical left ventricular diastolic dysfunction.

Magnetic resonance imaging·2026
Same journal

Bone marrow fat fraction and R2* in sickle cell disease: Associations with hemolysis, iron metabolism, and disease severity.

Magnetic resonance imaging·2026
See all related articles

Related Experiment Video

Updated: May 29, 2026

Tracing de novo Lipids using Stable Isotope Labeling LC-TIMS-TOF MS/MS
07:12

Tracing de novo Lipids using Stable Isotope Labeling LC-TIMS-TOF MS/MS

Published on: August 23, 2024

Mapping the double bonds in triglycerides.

Mark Bydder1, Olivier Girard, Gavin Hamilton

  • 1Department of Radiology, University of California San Diego, San Diego, CA 92103-8226, USA. mbydder@ucsd.edu

Magnetic Resonance Imaging
|August 27, 2011
PubMed
Summary
This summary is machine-generated.

This study introduces a new magnetic resonance imaging model to accurately estimate double bonds in triglycerides. The method is validated in phantoms and shows feasibility in human subjects for nutritional assessment.

More Related Videos

Arabidopsis thaliana Polar Glycerolipid Profiling by Thin Layer Chromatography (TLC) Coupled with Gas-Liquid Chromatography (GLC)
13:02

Arabidopsis thaliana Polar Glycerolipid Profiling by Thin Layer Chromatography (TLC) Coupled with Gas-Liquid Chromatography (GLC)

Published on: March 18, 2011

Profiling the Triacylglyceride Contents in Bat Integumentary Lipids by Preparative Thin Layer Chromatography and MALDI-TOF Mass Spectrometry
09:18

Profiling the Triacylglyceride Contents in Bat Integumentary Lipids by Preparative Thin Layer Chromatography and MALDI-TOF Mass Spectrometry

Published on: September 5, 2013

Related Experiment Videos

Last Updated: May 29, 2026

Tracing de novo Lipids using Stable Isotope Labeling LC-TIMS-TOF MS/MS
07:12

Tracing de novo Lipids using Stable Isotope Labeling LC-TIMS-TOF MS/MS

Published on: August 23, 2024

Arabidopsis thaliana Polar Glycerolipid Profiling by Thin Layer Chromatography (TLC) Coupled with Gas-Liquid Chromatography (GLC)
13:02

Arabidopsis thaliana Polar Glycerolipid Profiling by Thin Layer Chromatography (TLC) Coupled with Gas-Liquid Chromatography (GLC)

Published on: March 18, 2011

Profiling the Triacylglyceride Contents in Bat Integumentary Lipids by Preparative Thin Layer Chromatography and MALDI-TOF Mass Spectrometry
09:18

Profiling the Triacylglyceride Contents in Bat Integumentary Lipids by Preparative Thin Layer Chromatography and MALDI-TOF Mass Spectrometry

Published on: September 5, 2013

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Nutritional Science

Background:

  • Triglycerides are key lipids in nutrition and metabolism.
  • Accurate quantification of triglyceride unsaturation is important for health assessment.
  • Current methods for assessing triglyceride double bonds are limited.

Purpose of the Study:

  • To develop and validate a magnetic resonance imaging (MRI) model for estimating the number of double bonds in triglyceride molecules.
  • To enable reliable estimation using limited time points from chemical shift imaging.
  • To assess the feasibility of this technique in vivo.

Main Methods:

  • A theoretical model was developed to estimate double bonds in triglycerides using MRI.
  • The model incorporated prior knowledge from the US Department of Agriculture (USDA) to constrain triglyceride properties.
  • Validation was performed using oil phantoms and a feasibility scan in a human subject.

Main Results:

  • The MRI model demonstrated reliable estimation of double bonds from a small number of time points.
  • Validation in oil phantoms showed strong agreement with USDA reference values (correlation 0.95, P=.0003).
  • Feasibility was confirmed in a human subject using a 43-second breath-hold scan.

Conclusions:

  • The developed MRI model provides a non-invasive method for quantifying triglyceride unsaturation.
  • This technique has potential applications in nutritional assessment and metabolic studies.
  • The model's accuracy and feasibility suggest its utility in clinical and research settings.