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Collecting Hair Samples for Hair Cortisol Analysis in African Americans
06:01

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Published on: June 10, 2018

Hair testing is taking root.

Gail Audrey Ann Cooper1

  • 1Forensic Medicine and Science, University of Glasgow, Glasgow G12 8QQ, UK. gail.cooper@glasgow.ac.uk

Annals of Clinical Biochemistry
|August 27, 2011
PubMed
Summary

Hair testing offers a historical drug exposure profile, complementing traditional toxicology methods. Laboratories must address challenges like quality control and low concentrations for successful implementation.

Area of Science:

  • Forensic Toxicology
  • Analytical Chemistry

Background:

  • Growing demand for expanded toxicology services.
  • Hair analysis offers advantages: ease of collection, stability, and historical exposure data.
  • Hair testing is increasingly adopted in forensic toxicology due to its success in medicolegal cases.

Purpose of the Study:

  • To highlight the benefits and challenges of implementing hair testing in toxicology laboratories.
  • To guide laboratories on the necessary considerations beyond adapting existing methodologies.
  • To emphasize the importance of avoiding over-interpretation of hair testing results.

Main Methods:

  • Review of hair as a matrix in toxicology.
  • Discussion of advantages and challenges compared to blood or urine testing.

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  • Consideration of laboratory requirements for hair analysis.

    • Main Results:

    • Hair analysis provides a stable, historical record of drug exposure.
    • Implementation requires addressing challenges: quality control materials, sample handling, and instrument sensitivity.
    • Potential pitfalls include over-interpretation of findings.

    Conclusions:

    • Hair testing is a valuable complementary tool in forensic toxicology.
    • Laboratories must prepare for specific challenges associated with hair analysis.
    • Careful interpretation is crucial for accurate toxicological assessments.