Related Experiment Video
Updated: May 29, 2026

07:56
Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
Acute pediatric stroke: contributors to institutional cost
Colin M Turney1, Wei Wang, Eric Seiber
1Division of Neurology, Nationwide Children's Hospital, Columbus, OH, USA.
Stroke
|August 27, 2011
Summary
Pediatric stroke care costs are detailed, with nursing and imaging as primary drivers. Hemorrhagic strokes incur higher hospital costs than ischemic strokes.
Area of Science:
- Pediatric Neurology
- Healthcare Economics
- Hospital Administration
Background:
- Limited data exists on the specific cost sources for pediatric stroke care.
- Previous research focused on overall costs, not granular expense breakdowns.
Purpose of the Study:
- To identify and rank the sources of acute hospital care costs for pediatric stroke.
- To analyze cost differences between hemorrhagic and ischemic pediatric strokes.
Main Methods:
- Utilized the Pediatric Health Information System administrative database (2003-2009).
- Analyzed 1667 pediatric stroke cases, categorizing costs into 7 groups.
- Adjusted total costs for inflation using the US Consumer Price Index.
Main Results:
- Median total cost for pediatric stroke was $19,548.
- "Other/nursing" was the highest cost category, followed by imaging, laboratory, and pharmacy.
- Hemorrhagic strokes ($24,843) were more costly than ischemic strokes ($16,954).
Conclusions:
- This study provides the first in-depth cost analysis for pediatric stroke care.
- Nursing and imaging costs are key areas for potential cost containment strategies.
- Optimizing imaging use and length of inpatient stays may reduce overall costs.
Related Concept Videos
Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Stroke: Introduction and Types
A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
Secondary Spinal Cord Injury llI: Pathophysiology
Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...

