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Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
Published on: February 15, 2022
Classification by thresholding
1NASA Johnson Space Center, Houston, TX 77058.
Abstract:
A procedure is given which substantially reduces the processing time needed to perform maximum likelihood classification on large data sets. The given method uses a set of fixed thresholds which, if exceeded by one probability density function, makes it unnecessary to evaluate a competing density function. Proofs are given of the existence and optimality of these thresholds for the class of continuous, unimodal, and quasi-concave density functions (which includes the multivariate normal), and a method for computing the thresholds is provided for the specifilc case of multivariate normal densities. An example with remote sensing data consisting of some 20 000 observations of four-dimensional data from nine ground-cover classes shows that by using thresholds, one could cut the processing time almost in half.

