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Updated: May 29, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
A general expert system design for diagnostic problem solving
Abstract:
Existing expert systems have a high percentage agreement with experts in a particular field in many situations. However, in many ways their overall behavior is not like that of a human expert. These areas include the inability to give flexible, functional explanations of their reasoning processes, and the failure to degrade gracefully when dealing with problems at the periphery of their knowledge. These two important shortcomings can be improved when the right knowledge is available to the system. This paper presents an expert system design, called the integrated diagnostic model (IDM), that integrates two sources of knowledge, a shallow, reasoning-oriented, experiential knowledge base and a deep, functionally oriented, physical knowledge base. To demonstrate the IDM's usefulness in the problem area of diagnosis and repair, an implementation in the mechanical domain is described.
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