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Updated: May 29, 2026

Development and Validation of a Quantitative PCR Method for Equid Herpesvirus-2 Diagnostics in Respiratory Fluids
Published on: March 17, 2016
Streptococcus equi subspecies equi infection (strangles) in horses
1University of Pennsylvania, USA.
Strangles, a contagious respiratory infection in horses caused by Streptococcus equi subspecies equi, presents with fever and swollen lymph nodes. Early detection and strict hygiene are crucial for controlling outbreaks and preventing recurrence.
Area of Science:
- Equine infectious diseases
- Bacterial respiratory infections
- Veterinary immunology
Background:
- Streptococcus equi subspecies equi causes strangles, a highly contagious upper respiratory infection in horses.
- Transmission occurs via inhalation or direct contact with infected discharge.
- Clinical signs include fever, depression, and lymph node enlargement, potentially causing respiratory distress.
Purpose of the Study:
- To summarize the transmission, clinical presentation, complications, and control of Streptococcus equi subspecies equi infections.
- To highlight the importance of carrier detection for disease management.
Main Methods:
- Review of existing literature on Streptococcus equi subspecies equi.
- Analysis of transmission routes and clinical manifestations.
- Evaluation of control strategies and diagnostic importance.
Main Results:
- Strangles leads to significant morbidity in horses.
- Complications such as purpura hemorrhagica and metastatic abscessation can occur.
- Effective control relies on isolation, hygiene, and carrier identification.
Conclusions:
- Strangles poses a significant threat to equine health.
- Strict biosecurity measures are essential for outbreak control.
- Identifying carriers is critical to prevent strangles re-emergence on farms.
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