Related Experiment Video
Updated: May 29, 2026

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
Published on: May 4, 2012
[The alteration of proteins glycosylation in liver diseases]
1Uniwersytet Medyczny w Białymstoku, Zaklad Diagnostyki Biochemicznej. chrostek@umwb.edu.pl
Abstract:
The changes in protein glycosylation play an important role in the pathogenesis and progression of various liver diseases. In the different types of liver diseases the same type of alterations seems to reappear. They are: hyperfucosylation, increased branching and the presence of increased bisecting N-acetylglucosamine of glycans. For these modification are responsible the activities of different glycosyltransferases, that are generally increased in liver diseases. However, the changes in the glycans structure of serum proteins are characteristic in the liver diseases of different etiologies and therefore could be potentially used in the diagnostics of liver pathology
Related Concept Videos
Proteoglycans
Protein Glycosylation
Glycosylation occurs in...
Oligosaccharide Assembly
Multiple sugar molecules that may or may...
Inborn Errors of Metabolism
Cell Specific Gene Expression
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
