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Updated: May 29, 2026
06:55
An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
Published on: December 2, 2015
[Depression and cardiovascular diseases in the elderly]
Lucretia Angheel1, Rodica Ghiuru, Cristina-Maria Gavrilescu
1Universităţii de Medicină şi Farmacie Gr. T. Popa Iaşi, Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Medicină.
Summary
Depression is linked to cardiovascular disease, with higher cholesterol and blood pressure seen in severe cases. This highlights depression as an independent risk factor for cardiovascular events.
Area of Science:
- Geriatric Medicine
- Cardiology
- Psychiatry
Context:
- Cardiovascular disease (CVD) is a leading cause of mortality globally.
- Depression is a common comorbidity in elderly populations.
- The relationship between depression and CVD risk factors requires further investigation.
Purpose:
- To investigate the association between depression and cardiovascular disease.
- To determine if depression is an independent risk factor for cardiovascular events.
- To analyze the correlation between depression severity and cardiovascular risk factors.
Summary:
- A study of 413 patients assessed depression using the Geriatric Depression Scale (GDS) and evaluated cardiovascular risk factors.
- Results indicated a higher prevalence of dyslipidemia, obesity, and depression in women.
- Severe depression correlated with elevated cholesterol, blood pressure, and increased cardiovascular risk.
Impact:
- Depression is identified as an independent risk factor for cardiovascular events.
- Cardiovascular risk factors escalate with depression severity, necessitating comprehensive patient evaluation.
- Individualized treatment strategies are crucial for managing comorbidities and improving quality of life in elderly patients with depression.
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