Related Experiment Video
Updated: May 29, 2026
04:33
Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
[Macroscopic and microscopic lesions in bronchial asthma].
Adriana Grigoraş1, Cornelia Amălinei, Raluca Balan
1Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Medicină, Disciplina de Histologie.
Summary
This study reveals that bronchial asthma involves significant airway inflammation and structural changes. Bronchoscopy with biopsy confirmed macroscopic and microscopic lesions, crucial for assessing asthma severity and airway remodeling.
Area of Science:
- Pulmonology
- Pathology
Context:
- Bronchial asthma is a chronic inflammatory airway disease.
- Characterized by reversible airflow obstruction and bronchial hyperresponsiveness.
- Requires detailed assessment of airway lesions for effective management.
Purpose:
- To evaluate macroscopic and microscopic airway lesions in bronchial asthma patients.
- Utilized bronchoscopy with biopsy for comprehensive analysis.
- Correlated findings with asthma severity classifications (GINA).
Summary:
- Endoscopic findings included edema, congestion, stenosis, and mucus hypersecretion.
- Microscopic examination revealed epithelial changes, basement membrane thickening, inflammation, and hypertrophy.
- 23.68% of patients had asthma for over 15 years.
Impact:
- Bronchoscopy provides valuable information on airway mucosal changes.
- Microscopic examination via biopsy remains the gold standard for assessing bronchial wall remodeling.
- Highlights the importance of integrated diagnostic approaches in asthma management.
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