Related Experiment Video
Updated: May 29, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
[Corneal crosslinking as treatment for progressive keratoconus]
Nayyirih G Tahzib1, A Gonnie van der Leij
1Universitair Medisch Centrum Utrecht, afd. Oogheelkunde, Utrecht, the Netherlands. n.g.tahzib@umcutrecht.nl
Abstract:
Corneal crosslinking (CXL) is a relatively new medical treatment for progressive cases of keratoconus. This disease is characterized by corneal deformation and thinning, leading to corneal surface distortion and visual disability, mainly occurring in young patients. CXL was first applied in humans in 1999 and is internationally considered the standard treatment for cases of rapidly progressing keratoconus. The treatment protocol consists of corneal epithelial removal, the administration of riboflavin eye drops and irradiation with ultraviolet-A light. The primary goal of CXL is to mechanically stabilize and strengthen the cornea. CXL plays an important role in the treatment of keratoconus and may in the future delay or eliminate the need for a corneal transplantation.
More Related Videos
05:56Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Published on: April 3, 2016
12:25Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking (TXL) for Myopia
Published on: January 6, 2018
Related Concept Videos
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...