Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High Rates of Permanent Pacemaker Implantation After Left-Sided Cardiac Surgery in Adults with Congenital Heart Disease.

Heart rhythm·2026
Same author

The Society of Thoracic Surgeons (STS)/World Society for Pediatric and Congenital Heart Surgery (WSPCHS)/European Congenital Heart Surgeons Association (ECHSA) Expert Opinion on the Role of Exercise Testing in Determining Optimal Timing of Pulmonary Valve Replacement in Tetralogy of Fallot.

The Annals of thoracic surgery·2026
Same author

A Call for Investment in Sponsorship, Apprenticeship, and Mentorship: Ensuring the Future of Congenital Heart Surgery.

The Annals of thoracic surgery·2026
Same author

Successful explantation of an EDWARDS INTUITY rapid deployment valve with concomitant annular enlargement.

Journal of cardiothoracic surgery·2026
Same author

Single Ventricle Physiology May Not Preclude Cardiac Repair in the Setting of Congenital Diaphragmatic Hernia.

World journal for pediatric & congenital heart surgery·2026
Same author

Autograft Enlargement After the Ross Procedure in Pediatric Patients: Somatic Growth or Pathologic Dilatation?

World journal for pediatric & congenital heart surgery·2026

Related Experiment Video

Updated: May 29, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Small prosthesis size in aortic valve replacement does not affect mortality.

Damien J LaPar1, Gorav Ailawadi, Castigliano M Bhamidipati

  • 1Department of Surgery, University of Virginia Health System, School of Medicine, Charlottesville, Virginia 22908, USA.

The Annals of Thoracic Surgery
|August 30, 2011
PubMed
Summary

Small aortic valve prostheses in aortic valve replacement (AVR) do not independently increase operative mortality. Higher risks are linked to patient comorbidities and surgical factors, not just prosthesis size.

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Related Experiment Videos

Last Updated: May 29, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Patient Outcomes

Background:

  • Small aortic valve (AV) prostheses have been linked to poorer outcomes in aortic valve replacement (AVR).
  • This study investigates whether small AV prostheses independently affect operative mortality or if comorbidities are the primary drivers.

Purpose of the Study:

  • To determine if small aortic valve prosthesis size is an independent predictor of operative mortality in primary AVR.
  • To identify other risk factors contributing to mortality and morbidity in AVR patients.

Main Methods:

  • Analysis of 4,621 primary AVR operations across 13 centers (2003-2008).
  • Stratification of patients into small (≤21 mm) and standard (≥23 mm) AV prosthesis groups.
  • Univariate and multivariable regression analyses to assess the impact of prosthesis size and other factors on outcomes.

Main Results:

  • Small AV prostheses were associated with higher rates of major complications, mortality, longer hospital stays, and increased costs.
  • However, multivariable analysis revealed that small prosthesis size and female gender were not independent predictors of operative mortality.
  • Advanced age, longer cardiopulmonary bypass time, and aortic annular enlargement were significant predictors of operative mortality.

Conclusions:

  • Small aortic valve prosthesis size does not independently increase operative mortality after primary AVR.
  • Increased morbidity and mortality in patients receiving small prostheses are attributed to confounding preoperative and operative risk factors.
  • Aortic annular enlargement may not consistently reduce mortality in all cases.