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Published on: September 26, 2018
Burden of systemic hypertension in patients admitted to cardiology hospitalization units
Alberto Cordero1, Vicente Bertomeu-González, José Moreno-Arribas
1Cardiology Department, Hospital Universitario de San Juan, Alicante, Spain. acorderofort@gmail.com
Insights
Hypertension significantly increases readmission and mortality risks in cardiology patients. This study found that patients with a history of hypertension experienced higher rates of cardiac rehospitalization and death within one year.
Area of Science:
- Cardiology
- Public Health
Background:
- Hypertension is a leading cardiovascular risk factor.
- Conflicting evidence exists regarding hypertension's impact on prognosis in patients with existing cardiovascular disease.
Purpose of the Study:
- To evaluate the effect of hypertension on readmission and one-year mortality in cardiology inpatients.
Main Methods:
- Prospective study of 1,007 cardiology inpatients with 1-year follow-up.
- Data collected included clinical history, risk factors, and discharge diagnoses.
- Multivariate analysis was used to identify independent risk factors.
Main Results:
- 69% of patients had a history of hypertension, presenting with older age and more comorbidities.
- Hypertensive patients showed significantly higher rates of cardiac rehospitalization (31.1% vs 17.9%) and total mortality (17.4% vs 9.3%).
- Hypertension was an independent predictor of cardiovascular readmission and a combined endpoint of readmission or mortality.
Conclusions:
- Hypertension is highly prevalent in cardiology admissions.
- Pre-existing hypertension is associated with increased one-year rehospitalization and mortality risks in this patient population.
Abstract:
Hypertension is 1 of the most prevalent cardiovascular risk factors; nevertheless, some studies have reported that the antecedent of hypertension does not impair prognosis in patients with established cardiovascular disease. The objective of this study was to describe the impact of hypertension on readmission and 1-year mortality in patients admitted to a single cardiology hospitalization unit. All consecutive hospitalizations in a single cardiology department through 10 months were included, and 1-year follow-up was performed. Clinical antecedents, risk factors, and main discharge diagnoses were collected. A total of 1,007 patients were included (mean age 71.1 ± 13.5 years). The antecedent of hypertension was present in 69.0%, and these patients had older mean age and higher prevalence of risk factors and previous cardiovascular disease. No differences in hospital discharge main diagnoses were observed according to the antecedent of hypertension. During a mean follow-up period of 404.82 ± 122.2 days, patients with hypertension had higher rates of rehospitalization for cardiac causes (31.1% vs 17.9%, p = 0.01) and of total (17.4% vs 9.3%, p <0.01) and cardiovascular (13.9% vs 5.9%, p <0.01) mortality. Multivariate analysis identified the antecedent of hypertension as an independent risk factor for cardiovascular readmission (hazard ratio 1.46, 95% confidence interval 1.10 to 1.98) and the combined end point of readmission or mortality (hazard ratio 1.45, 95% confidence interval 1.12 to 1.88); no independent association was observed for total mortality. In conclusion, hypertension was present in most patients admitted to a cardiology unit, and they had higher rates of rehospitalization and mortality at 1-year follow-up.
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