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Mesenteric myofibroblastic tumor: NSAID therapy after incomplete resection
1Service de chirurgie, hôpital militaire de Ouakam, Dakar, Senegal. dballa33@yahoo.fr
Journal of Visceral Surgery
|August 30, 2011
Summary
Myofibroblastic tumors, rare inflammatory lesions, can recur after surgery. In a mesenteric myofibroblastic tumor case, anti-inflammatory drugs successfully regressed the tumor when surgery was not feasible.
Area of Science:
- Oncology
- Pathology
Background:
- Myofibroblastic tumors are inflammatory lesions of soft tissue and viscera with unclear etiopathology.
- Their neoplastic or inflammatory, benign or malignant nature remains debated due to infiltration and metastasis potential.
Observation:
- A 59-year-old male presented with a mesenteric myofibroblastic tumor.
- Complete surgical resection was not feasible due to extensive local infiltration.
Findings:
- The tumor recurred three months post-surgery.
- Treatment with steroidal and non-steroidal anti-inflammatory medications (NSAIDs) led to significant clinical and radiologic tumor regression.
Implications:
- This case suggests a potential therapeutic role for anti-inflammatory medications in managing recurrent myofibroblastic tumors, especially when surgical options are limited.
- Further research into the inflammatory pathways of myofibroblastic tumors may reveal novel treatment strategies.
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