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Updated: May 29, 2026

Erosion Identification in Metacarpophalangeal Joints in Rheumatoid Arthritis using High-Resolution Peripheral Quantitative Computed Tomography
Published on: October 6, 2023
Step performance in persons with rheumatoid arthritis: a case-control study.
Ellen Smulders1, Wim van Lankveld, Florieke Eggermont
1Department of Rheumatology, Sint Maartenskliniek, Nijmegen, the Netherlands.
Patients with rheumatoid arthritis (RA) exhibit slower movement times and reduced push-off force during quick stepping, increasing fall risk. They also report lower balance confidence and greater fear of falling.
Area of Science:
- Rheumatology
- Biomechanics
- Gerontology
Background:
- Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting joints.
- Falls are a significant concern for individuals with RA, impacting mobility and quality of life.
Purpose of the Study:
- To identify specific factors contributing to falls in patients with rheumatoid arthritis (RA).
- To compare motor performance and psychological factors related to falls between RA patients and healthy controls.
Main Methods:
- A case-control study involving 15 patients with RA and 15 age- and sex-matched controls.
- Assessment of quick stepping task performance, including reaction times (RTs) and movement times (MTs).
- Evaluation of manual task performance, balance confidence, fear of falling, and activity levels through questionnaires.
Main Results:
- Patients with RA demonstrated significantly longer movement times (MTs) and lower push-off force and step velocity during a quick step task.
- Delayed reaction times (RTs) and movement times (MTs) were observed in a manual task for RA patients.
- RA patients reported significantly lower balance confidence and higher fear of falling compared to controls, with no difference in activity levels.
Conclusions:
- Impaired quick stepping execution, characterized by delayed movement times and reduced velocity, may contribute to an increased fall risk in RA patients.
- Lower balance confidence and increased fear of falling are prevalent in RA patients and are significant psychological contributors to higher fall risk.
- These findings highlight the need for interventions addressing both motor deficits and psychological factors to mitigate fall risk in rheumatoid arthritis.
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