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Updated: May 29, 2026
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Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
Published on: August 1, 2018
The prefrontal cortex: comparative architectonic organization in the human and the macaque monkey brains
Michael Petrides1, Francesco Tomaiuolo, Edward H Yeterian
1Montreal Neurological Institute, Department of Neurology and Neurosurgery, Montreal, QC, Canada. michael.petrides@mcgill.ca
Summary
Comparing human and macaque prefrontal cortex cytoarchitecture reveals nomenclature discrepancies. This study resolves these inconsistencies, enabling better translation of nonhuman primate research to human neuroimaging findings.
Area of Science:
- Neuroscience
- Comparative Anatomy
Background:
- Brodmann's map (1909) is standard for human cerebral cortex cytoarchitecture and neuroimaging.
- Walker's map (1940) is commonly used for macaque prefrontal cortex but lacks human comparative basis.
Purpose of the Study:
- To outline discrepancies between human and macaque prefrontal cortex cytoarchitectonic maps.
- To resolve these inconsistencies for improved translation of nonhuman primate research to human neuroimaging.
Main Methods:
- Comparative investigation of macaque and human prefrontal cortex cytoarchitecture.
- Analysis of classical cytoarchitectonic maps (Brodmann, Walker).
Main Results:
- Identified inconsistencies in nomenclature and demarcation criteria between human and macaque prefrontal cortex maps.
- Established a basis for consistent terminology and area definition across species.
Conclusions:
- Discrepancies in classical maps hinder cross-species research translation.
- Comparative cytoarchitectonic studies enable accurate comparison of nonhuman primate and human brain findings.
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