Related Experiment Video
Updated: May 29, 2026

Isolation, Behavioral Identification, and Pathogenicity Assessment of Entomopathogenic Fungi from a Forest Wood Borer
Published on: September 29, 2023
Coprismycins A and B, neuroprotective phenylpyridines from the dung beetle-associated bacterium, Streptomyces sp
Seong-Hwan Kim1, Hyeonseok Ko, Hea-Son Bang
1Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
Abstract:
Two new phenylpyridines, named coprismycins A and B (1 and 2), and previously reported dipyridines (3-6) were isolated from a culture of Streptomyces sp. associated with the dung beetle, Copris tripartitus. The structures of the coprismycins (1 and 2) were elucidated by the analysis of 1D and 2D NMR spectra and mass, UV, and IR spectra. Coprismycins A-B (1 and 2) and dipyridines (5 and 6) displayed comparable neuroprotective effects against MPP(+) (1-methyl-4-phenylpyrimidium)-induced neurotoxicity in neuroblastoma SH-SY5Y cells.
Related Concept Videos
Bacterial Phylum Actinobacteria
Bacterial Phylum Planctomycetes
Production of Biopesticides
Microbial Interactions: Cooperation
Biological Methods for Microbial Control
Inhibitors of Gram-positive Cell Wall Synthesis

