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Assessment of red cell distribution width (RDW) in patients with coronary artery ectasia

Orhan Dogdu1, Fatih Koc, Nihat Kalay

  • 1Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey.

Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
|August 30, 2011
PubMed

Insights

Red cell distribution width (RDW) is elevated in patients with coronary artery ectasia (CAE). This simple blood test may serve as a reliable marker for diagnosing CAE.

Area of Science:

  • Cardiology
  • Hematology

Background:

  • Coronary artery ectasia (CAE) involves abnormal coronary artery dilation.
  • Red cell distribution width (RDW) quantifies red blood cell size heterogeneity.

Purpose of the Study:

  • To investigate red cell distribution width (RDW) levels in patients diagnosed with coronary artery ectasia (CAE).

Main Methods:

  • The study included 54 patients with CAE and 40 controls with normal coronary arteries.
  • Red cell distribution width (RDW) was measured using automated complete blood count on admission.

Main Results:

  • Patients with coronary artery ectasia (CAE) exhibited significantly higher red cell distribution width (RDW) compared to controls (P < .001).
  • High-sensitive C-reactive protein (hs-CRP) levels were also significantly elevated in the CAE group versus controls (P < .001).

Conclusions:

  • Red cell distribution width (RDW) and hs-CRP levels are significantly higher in patients with coronary artery ectasia (CAE).
  • RDW presents a reliable, simple, and inexpensive biomarker for identifying patients with coronary artery ectasia (CAE).
Abstract

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