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Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
Published on: February 21, 2018
Structure of the granulocyte macrophage colony-stimulating factor gene in patients with the myelodysplastic syndromes
J Boultwood1, G Abrahamson, V J Buckle
1Leukaemia Research Fund Molecular and Cytogenetic Haematology Unit, John Radcliffe Hospital, Headington, Oxford, England.
Abstract:
DNA samples from 76 patients with the myelodysplastic syndromes, including 10 cases with a partial deletion of the long arm of chromosome 5 (5q-), were examined for structural rearrangements of the granulocyte/macrophage colony-stimulating factor (GM-CSF) gene. No abnormalities were detected, indicating that structural aberrations of this gene are not a feature of the myelodysplastic syndromes.
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