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Related Experiment Videos

The amniotic fluid index in normal human pregnancy.

T R Moore1, J E Cayle

  • 1Department of Obstetrics and Gynecology, U.S. Naval Hospital, San Diego, CA.

American Journal of Obstetrics and Gynecology
|May 1, 1990
PubMed
Summary

This study establishes normative reference ranges for the amniotic fluid index (AFI) in normal pregnancies. AFI measurements should be interpreted using week-specific tables for accurate assessment of fetal well-being.

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Area of Science:

  • Obstetrics and Gynecology
  • Fetal Medicine
  • Diagnostic Imaging

Background:

  • Accurate assessment of amniotic fluid volume is crucial for monitoring fetal health.
  • The amniotic fluid index (AFI) is a common method for quantifying amniotic fluid.
  • Establishing reliable normative data is essential for interpreting AFI measurements.

Purpose of the Study:

  • To prospectively determine normative values for the amniotic fluid index (AFI) across gestation in normal pregnancies.
  • To assess interobserver and intraobserver variability in AFI measurements.
  • To provide week-specific reference ranges for AFI interpretation.

Main Methods:

  • Prospective study of 791 normal pregnancies.
  • Measurement of the four-quadrant sum of amniotic fluid pockets to calculate the AFI.
  • Logarithmic transformations used to establish mean and 90% confidence intervals for AFI at each gestational week.

Main Results:

  • Low interobserver (3.1%) and intraobserver (6.7%) variation in AFI measurements.
  • Normative data established for AFI throughout pregnancy, with specific ranges provided for term and postdates pregnancies.
  • Statistically significant differences in weekly AFI values highlight the need for gestational age-specific interpretation.

Conclusions:

  • This study provides comprehensive, week-specific normative data for the amniotic fluid index (AFI) in normal pregnancies.
  • Accurate interpretation of AFI requires comparison with gestational age-appropriate reference ranges.
  • The established data can aid clinicians in better assessing fetal well-being through amniotic fluid volume monitoring.

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