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Resolving natural product epimer spectra by matrix-assisted DOSY

Ralph W Adams1, Juan A Aguilar, Julia Cassani

  • 1School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.

Organic & Biomolecular Chemistry
|August 30, 2011
PubMed
Summary

Matrix-assisted DOSY NMR using beta-cyclodextrin successfully distinguished naringin epimers by altering their diffusion. This chiral method offers a new way to resolve epimer and enantiomer spectra without complex procedures.

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