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Related Experiment Videos

Evaluation of smallpox vaccination policy.

I Arita, J G Breman

    Bulletin of the World Health Organization
    |January 1, 1979
    PubMed
    Summary

    The Global Commission is verifying smallpox eradication. Reducing variola virus stocks in laboratories is crucial to prevent recurrence and stop smallpox vaccinations.

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    Area of Science:

    • Public Health
    • Infectious Disease Epidemiology
    • Virology

    Background:

    • The Global Commission for the Certification of Smallpox Eradication is verifying eradication in 31 countries.
    • The year 1979 is critical for declaring the world smallpox-free if no new cases are found.
    • Laboratory-associated smallpox cases highlight risks from remaining variola virus stocks.

    Purpose of the Study:

    • To assess the progress and challenges in global smallpox eradication efforts.
    • To evaluate the risks posed by variola virus stocks in laboratories.
    • To determine the justification for continued smallpox vaccination post-eradication.

    Main Methods:

    • Global surveillance activities to detect remaining smallpox cases.
    • Verification processes by the Global Commission for the Certification of Smallpox Eradication.
    • Assessment of scientific data on smallpox recurrence potential.

    Main Results:

    • Verification of smallpox eradication is underway in 31 countries.
    • Efforts are in progress to limit variola virus retention to four WHO collaborating centers by 1980.
    • Scientific evidence suggests a low likelihood of smallpox recurrence after eradication.

    Conclusions:

    • Continued smallpox vaccination is unjustifiable if eradication is verified, due to severe complications.
    • Terminating vaccination programs is expected to result in significant global cost savings.
    • Securing and reducing variola virus stocks is essential for global health security.

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