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Related Concept Videos

Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems related to...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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[Gastrointestinal changes in patients with systemic sclerosis].

Branimir Anić1

  • 1Zavod za klinicku imunologiju i reumatologiju, Kispatićeva 12, 10000 Zagreb.

Reumatizam
|August 31, 2011
PubMed
Summary

Systemic sclerosis commonly causes gastrointestinal (GI) complications. This study reviews the various GI manifestations and their management in patients with this autoimmune disease.

Area of Science:

  • Gastroenterology
  • Rheumatology
  • Internal Medicine

Context:

  • Systemic sclerosis is a chronic autoimmune disease characterized by fibrosis of the skin and internal organs.
  • Gastrointestinal (GI) involvement is a frequent and often debilitating complication of systemic sclerosis.
  • Understanding the spectrum of GI changes is crucial for patient management.

Purpose:

  • To present the diverse gastrointestinal changes observed in patients with systemic sclerosis.
  • To outline the diagnostic approaches for GI manifestations in systemic sclerosis.
  • To discuss current therapeutic strategies for managing GI complications.

Summary:

  • Systemic sclerosis can affect any part of the GI tract, from the esophagus to the rectum.
  • Common GI symptoms include dysphagia, heartburn, early satiety, bloating, constipation, diarrhea, and fecal incontinence.

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  • Motility disorders, malabsorption, and vascular abnormalities are key pathophysiological mechanisms.

    • Impact:

    • Improved recognition and diagnosis of GI complications in systemic sclerosis.
    • Enhanced patient care through targeted management of GI symptoms.
    • Potential for improved quality of life for individuals with systemic sclerosis.