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Updated: May 29, 2026

Transient Middle Cerebral Artery Occlusion Model of Stroke
Published on: August 11, 2023
Short-term risk and predictors of stroke after transient ischemic attack
Mohamed Al-Khaled1, Christine Matthis, Jürgen Eggers
1Department of Neurology, University of Lübeck, Germany. Mohamed.al-khaled@neuro.uni-luebeck.de
Background:
Transient ischemic attack (TIA) is a marker of stroke, especially in the early phase following this event. The aims of this study are to determine the short-term risk of stroke and to evaluate the independent predictors of stroke in patients with TIA who are hospitalized within 48 hours after symptom onset.
Methods:
During a 36-month period (beginning in November 2007), 3554 patients (mean age: 70.5 ± 13 years; 49.9% female; mean NIHSS score: 1.4 ± 2.5) from 15 hospitals suffering from TIA were prospectively evaluated.
Results:
Of the 3554 patients, 43 (1.2%) suffered from stroke during hospitalization (6.5 ± 4.3 days). We identified the following independent predictors for stroke after TIA: male sex (odds ratio [OR], 2.5; 95% confidence interval [CI], 1.3-5; P=0.008), age ≥65 years (OR, 4.7; 95% CI, 1.4-15; P=0.01), hyperlipidemia (OR, 2.4; 95% CI, 1.2-4.8; P=0.015), and dysarthria (OR, 2; 95% CI, 1.1-5.0; P=0.038).
Conclusion:
Patient characteristics (male sex, age, and hyperlipidemia) and TIA symptom (dysarthria) may be useful in defining stroke after TIA in patients who were hospitalized with TIA.
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