Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Subtle language deficits in WAB-recovered patients at 12 months after left-hemisphere stroke.

medRxiv : the preprint server for health sciences·2026
Same author

Acute-Phase Machine Learning Prediction of 12-Month Aphasia and Discourse Recovery.

medRxiv : the preprint server for health sciences·2026
Same author

Revisiting Western Aphasia Battery-Revised in the Context of Mild Impairment.

American journal of speech-language pathology·2026
Same author

Health economics evaluation of artificial intelligence in the field of oncology: a scoping review.

Health economics review·2026
Same author

White matter predictors of cerebellar tDCS treatment effects in aphasia rehabilitation.

Frontiers in neurology·2026
Same author

Gradation of Prolonged Venous Transit on Perfusion Imaging Highlights the Association of Deep Venous Drainage Impairment with Unfavorable Functional Outcome in Successfully Reperfused Anterior Circulation Large-Vessel-Occlusion Stroke.

AJNR. American journal of neuroradiology·2026

Related Experiment Video

Updated: May 29, 2026

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Validating age-related functional imaging changes in verbal working memory with acute stroke.

Timothy B Meier1, Lin Naing, Lisa E Thomas

  • 1Neuroscience Training Program, University of Wisconsin-Madison, USA. tbmeier@wisc.edu

Behavioural Neurology
|August 31, 2011
PubMed
Summary
This summary is machine-generated.

Older adults require both brain hemispheres for verbal memory tasks, unlike younger adults who primarily use one. Stroke patients showed this bilateral necessity, impacting retrieval time in older individuals.

More Related Videos

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Related Experiment Videos

Last Updated: May 29, 2026

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
09:01

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neurology

Background:

  • Older adults often show reduced hemispheric asymmetry in brain activity during cognitive tasks compared to younger adults (Hemispheric Asymmetry Reduction in Older Adults model).
  • Functional imaging shows brain activation but cannot determine necessity of brain regions for task performance.

Purpose of the Study:

  • To test if older adults need bilateral brain activation for a verbal working memory task typically lateralized in younger adults.
  • To investigate the necessity of brain hemispheres in verbal working memory using stroke patient data.

Main Methods:

  • Compared behavioral data from younger and older adults with acute unilateral stroke.
  • Included younger and older transient ischemic attack (TIA) patients as controls.
  • Administered a self-paced verbal item-recognition task to assess verbal working memory.

Main Results:

  • Older stroke patients, regardless of hemisphere affected, exhibited more verbal working memory deficits than older TIA patients.
  • Older stroke patients primarily showed deficits in retrieval time.
  • Younger stroke patients predominantly displayed accuracy deficits.

Conclusions:

  • Bilateral brain activity appears necessary for older adults to perform verbal working memory tasks effectively.
  • Hemispheric asymmetry reduction in older adults may reflect a compensatory mechanism for cognitive tasks.