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Hypertension in the elderly
Blas Gil-Extremera1, Pedro Cía-Gómez
1Service of Internal Medicine, Hypertension and Lipid Unit, "San Cecilio" University Hospital, Granada, Spain.
International Journal of Hypertension
|August 31, 2011
Summary
Elderly hypertension treatment significantly benefits aged patients by improving blood pressure and reducing cardiovascular risks. Combination therapy, like nitrendipine plus enalapril, may offer enhanced advantages.
Area of Science:
- Gerontology
- Cardiovascular Medicine
- Pharmacology
Background:
- Increasing incidence of hypertension in Western elderly populations.
- Hypertension as a leading cause of cardiovascular morbidity and mortality.
Purpose of the Study:
- To review clinical trial findings on hypertension management in the elderly.
- To highlight the benefits of pharmacological treatment in aged hypertensive patients.
Main Methods:
- Analysis of significant clinical trials (e.g., SYST-EUR, HYVET, CONVINCE, VALUE).
- Evaluation of various antihypertensive treatments including nitrendipine, hydrochlorothiazide, perindopril, indapamide, verapamil, and valsartan.
Main Results:
- Demonstrated benefits of antihypertensive treatments in elderly patients.
- Improvements observed in blood pressure control and other cardiovascular risk factors.
- Evidence supporting the efficacy of specific drug classes and combination therapies.
Conclusions:
- Pharmacological treatment of hypertension is crucial for aged patients.
- Combination therapy, specifically nitrendipine plus enalapril, may provide superior benefits compared to monotherapy.
- Hypertension remains a prevalent and significant cardiovascular disorder in Western countries.
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