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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Predictors of developing significant mitral regurgitation following percutaneous mitral commissurotomy with inoue
Abdelfatah A Elasfar1, Hatem F Elsokkary
1Cardiology Department, Faculty of Medicine, Tanta University, Egypt.
Abstract:
Background. Despite the high technical expertise in percutaneous mitral commissurotomy (PMC), mitral regurgitation (MR) remains a major procedure-related complication. The aim of this work is to find out the most sensitive and applicable predictors of development of significant mitral regurgitation (SMR) following percutaneous mitral commissurotomy using Inoue balloon technique. Methods. We studied prospectively the preprocedural (clinical, echocardiography, and hemodynamic) and procedural predictors of significant mitral regurgitation (identified as increase of ≥2/4 grades of pre-PMC MR by color Doppler flow mapping) following valvuloplasty using Inoue balloon in 108 consecutive patients with severe mitral stenosis. Multiple stepwise logistic regression analysis was performed for variables found positive on univariate analysis to determine the most important predictor(s) of developing SMR. Results. The incidence of SMR following PMC using Inoue technique was 18.5% (10 patients). MV scoring systems were the only variables that showed significant differences between both groups (Group A without SMR and Group B with SMR). However, no clinical, other echocardiographic measurements, hemodynamic or procedural variables could predict the development of SMR. Using multiple regression analysis, the best predictive factor for the risk of SMR after Inoue BMV was the total MR-echo score with a cutoff point of 7 and a predictive percentage of 97.7%. Conclusions. The total MR-echo score is the only independent predictor of SMR following PMC using Inoue technique with a cutoff point of 7.
Insights
The total MR-echo score is the best predictor for significant mitral regurgitation after percutaneous mitral commissurotomy using the Inoue balloon technique. A score of 7 or higher indicates a high risk.
Area of Science:
- Cardiology
- Interventional Cardiology
- Echocardiography
Background:
- Percutaneous mitral commissurotomy (PMC) is a complex procedure.
- Mitral regurgitation (MR) is a frequent complication of PMC.
- Identifying predictors of significant MR (SMR) post-PMC is crucial.
Purpose of the Study:
- To identify sensitive and applicable predictors of SMR after Inoue balloon technique PMC.
- To evaluate preprocedural and procedural factors influencing SMR development.
Main Methods:
- Prospective study of 108 patients with severe mitral stenosis undergoing Inoue balloon PMC.
- Analysis of preprocedural (clinical, echocardiographic, hemodynamic) and procedural variables.
- Multivariable logistic regression to determine SMR predictors.
Main Results:
- SMR incidence was 18.5% (10 patients).
- Only MV scoring systems differed significantly between SMR and non-SMR groups.
- The total MR-echo score was the sole independent predictor of SMR (cutoff 7, 97.7% predictive value).
Conclusions:
- The total MR-echo score is the only independent predictor of SMR post-Inoue PMC.
- A total MR-echo score of 7 predicts SMR development with high accuracy.
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