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Calcium and vitamin d supplementation in men
Evelien Gielen1, Steven Boonen, Dirk Vanderschueren
1Division of Geriatric Medicine, Leuven University Hospital, Herestraat 49, 3000 Leuven, Belgium.
Journal of Osteoporosis
|August 31, 2011
Summary
Calcium and vitamin D supplements effectively treat secondary hyperparathyroidism and prevent fractures, especially in at-risk groups. Optimal benefits are seen with 1200mg calcium and 800 IU vitamin D daily, though calcium alone may pose cardiovascular risks.
Area of Science:
- Endocrinology
- Nutritional Science
- Geriatrics
Background:
- Calcium and vitamin D supplements are standard for secondary hyperparathyroidism and osteoporotic fracture prevention.
- Efficacy is proven when targeting individuals with documented deficiencies.
Purpose of the Study:
- To review the role of calcium and vitamin D supplementation in managing secondary hyperparathyroidism and preventing fractures.
- To identify specific populations that benefit most from supplementation.
- To assess optimal dosages and potential risks associated with supplementation.
Main Methods:
- Review of existing literature and meta-analytic data on calcium and vitamin D supplementation.
- Analysis of antifracture efficacy and safety profiles.
Main Results:
- Supplementation effectively reverses secondary hyperparathyroidism and reduces fracture risk.
- Elderly, institutionalized, osteoporotic, and glucocorticoid-treated individuals are key target groups.
- Optimal daily intake is 1000-1200mg calcium with 800 IU vitamin D.
- Calcium alone may be linked to cardiovascular risks, unlike vitamin D.
Conclusions:
- Calcium and vitamin D supplementation is beneficial for specific populations, particularly when deficiencies are present.
- Adherence to recommended dosages is crucial for maximizing clinical benefits.
- Potential cardiovascular risks associated with calcium-only supplements warrant consideration.
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