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Published on: August 2, 2024
Office hysteroscopy study in consecutive miscarriage patients.
Carlos Augusto Bastos de Souza1, Carla Schmitz, Vanessa Krebs Genro
1Department of Gynecology and Obstetrics, Clinical Hospital, Porto Alegre, Porto Alegre, RS, Brazil. souza.cab@gmail.com
Summary
Recurrent miscarriages are often linked to uterine abnormalities. Diagnostic hysteroscopy revealed a high prevalence of uterine cavity issues in women with multiple miscarriages, though the number of miscarriages did not alter the abnormality type.
Area of Science:
- Reproductive Medicine
- Gynecological Surgery
Background:
- Recurrent pregnancy loss (RPL) affects a significant number of women.
- Uterine anatomical abnormalities are a known contributing factor to RPL.
Purpose of the Study:
- To determine the prevalence of uterine anatomical abnormalities in patients with recurrent miscarriages using office hysteroscopy.
- To compare the prevalence of these abnormalities between patients with two and those with three or more consecutive miscarriages.
Main Methods:
- A cross-sectional study involving 66 patients with at least two consecutive miscarriages.
- Patients were categorized into two groups: up to two miscarriages (Group A) and three or more miscarriages (Group B).
- Outpatient diagnostic hysteroscopy was performed to identify congenital or acquired uterine cavity abnormalities.
Main Results:
- Uterine abnormalities were detected in 33.3% of patients.
- Congenital abnormalities included arcuate, septate, and bicornuate uterus; acquired abnormalities included intrauterine adhesions, endometrial polyps, and uterine leiomyomas.
- A positive correlation was observed between hysteroscopic findings and the number of miscarriages (r = 0.31; p = 0.02).
Conclusions:
- Office hysteroscopy is effective in diagnosing a high prevalence of uterine cavity abnormalities in patients with recurrent miscarriages.
- The prevalence and distribution of uterine lesions did not significantly differ based on the number of recurrent miscarriages (two vs. three or more).

