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Updated: May 29, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Antibiotic prescription in a teaching hospital: a brief assessment
Marcelo Carneiro1, Tanise Ferraz, Marina Bueno
1Hospital Infection Control of Hospital Santa Cruz, Santa Cruz do Sul, RS, Brazil. carneiromarcelo@yahoo.com.br
Objective:
Antimicrobials are used interchangeably in medical practice, contributing to the emergence of resistant microbial strains.
Methods:
This study describes the antimicrobial audit performed by forecasting analysis of medical records of 846 patients at the Hospital Santa Cruz, Santa Cruz do Sul - Rio Grande do Sul - Brazil.
Results:
Of the patients studied, 134 (15.8%) received antimicrobials. The audit was conducted interactively, with intervention and discussion with the prescriber. Considering the presumptive diagnosis and prescribed drug, it was verified that 74.6% of patients on antimicrobials received what was considered the first choice treatment. Inadequate antimicrobial agent for clinical diagnosis (5.2%) and lack of adjustment for renal function (43.7%) were the most frequent errors.
Conclusion:
A strategic plan aimed at the rational use of antimicrobials based on educational and interventionist practices can help the infection control professional to adjust the routines to improve healthcare quality.
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