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Deep cerebral venous system thrombosis in adults
L Milandre1, J F Pellissier, F Vincentelli
1Clinique Neurologique, CHU Timone, Marseille, France.
European Neurology
|January 1, 1990
Summary
Deep cerebral venous system thrombosis is often fatal, as illustrated by two adult cases. Early diagnosis via cerebral angiography is crucial, though autopsy confirmed venous occlusion and infarction in both patients.
Area of Science:
- Neurology
- Vascular Medicine
- Pathology
Background:
- Deep cerebral venous system thrombosis is a rare but serious condition.
- It can present with non-specific neurological symptoms, complicating diagnosis.
- Thrombosis of the galenic system, a part of the deep cerebral venous system, carries a high mortality rate.
Observation:
- Two adult patients presented with severe neurological symptoms.
- Initial presentations mimicked other neurological disorders like tumors or encephalitis.
- Diagnosis was confirmed antemortem in one case using cerebral angiography.
Findings:
- Autopsy revealed bilateral basal ganglia infarction in the first case.
- The second patient had hemorrhagic infarction of the thalamus and basal ganglia.
- Deep cerebral venous occlusion was confirmed post-mortem in both cases.
Implications:
- Thrombosis of the deep cerebral venous system, including the galenic system, carries a high mortality rate.
- Pathological changes and anticoagulation strategies are critical considerations.
- Improved diagnostic methods and timely intervention are essential for managing this condition.