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Updated: May 29, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
Published on: June 20, 2015
Twenty-four-hour repeatability of diurnal intraocular pressure patterns in glaucomatous and ocular hypertensive
Marcelo Hatanaka1, Mirko Babic, Remo Susanna Junior
1Department of Ophthalmology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. marcelohatanaka@gmail.com
Objective:
To verify the 24-hour repeatability of diurnal intraocular pressure patterns in glaucomatous and ocular hypertensive individuals.
Methods:
A prospective analysis of 88 eyes from 88 ocular hypertensive or open-angle glaucoma patients was conducted on diurnal tension curves obtained by the same examiner on two consecutive days. The intraclass correlation coefficient test was used for statistical analysis.
Results:
Eighty-eight eyes from 88 patients were analyzed. Fifty-seven patients (64.8%) were female. The mean age of all participants was 68.7 (SD 10.8, range 51-79) years. The intraclass correlation coefficient values for measurements at 8 AM, 11 AM, 2 PM, and 4 PM were 0.80, 0.82, 0.83, and 0.86, respectively (all intraclass correlation coefficient values, p<0.001).
Conclusion:
Diurnal intraocular pressure data collected on a single day characterize the diurnal intraocular pressure variability over 24 hours in primary open-angle glaucoma and ocular hypertensive patients.
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