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Updated: May 29, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Decision-making impairment in obsessive-compulsive disorder as measured by the Iowa Gambling Task
Felipe Filardi da Rocha1, Nathália Bueno Alvarenga, Leandro Malloy-Diniz
1Molecular Program, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte MG, Brazil. fil_bh@yahoo.com.br
Objective:
This study aims to evaluate the process of decision-making in patients with obsessive-compulsive disorder (OCD) using the Iowa Gambling Task (IGT). In addition, we intend to expand the understanding of clinical and demographic characteristics that influence decision-making.
Method:
Our sample consisted of 214 subjects (107 diagnosed with OCD and 107 healthy controls) who were evaluated on their clinical, demographic and neuropsychological features. Moreover, the Iowa Gambling Task (IGT), a task that detects and measures decision-making impairments, was used.
Results:
We found that OCD patients performed significantly worse on the IGT. Furthermore, features such as symptoms of anxiety did not influence IGT performance.
Conclusion:
Impaired decision-making seems to be a key feature of OCD. Given that OCD is a complex heterogeneous disorder, homogeneous groups are necessary for an accurate characterization of our findings.
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