Related Experiment Video
Updated: May 29, 2026

Purification and Quality Control of Recombinant Septin Complexes for Cell-Free Reconstitution
Published on: June 23, 2022
Spectrin-based skeleton as an actor in cell signaling
B Machnicka1, R Grochowalska, D M Bogusławska
1University of Zielona Góra, Zielona Góra, Poland.
Abstract:
This review focuses on the recent advances in functions of spectrins in non-erythroid cells. We discuss new data concerning the commonly known role of the spectrin-based skeleton in control of membrane organization, stability and shape, and tethering protein mosaics to the cellular motors and to all major filament systems. Particular effort has been undertaken to highlight recent advances linking spectrin to cell signaling phenomena and its participation in signal transduction pathways in many cell types.
Related Concept Videos
The Role of Actin and Myosin in Non-muscle Cells
Cytoskeletal Coordination in Cell Migration
Assembly of Signaling Complexes
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...
Skeleton and Calcium Homeostasis
Polarity of the Cytoskeleton
Cytoskeletal Accessory Proteins
