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Related Experiment Video

Updated: May 29, 2026

High-throughput Yeast Plasmid Overexpression Screen
08:57

High-throughput Yeast Plasmid Overexpression Screen

Published on: July 27, 2011

Advanced methods for high-throughput microscopy screening of genetically modified yeast libraries.

Yifat Cohen1, Maya Schuldiner

  • 1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

Methods in Molecular Biology (Clifton, N.J.)
|August 31, 2011
PubMed
Summary

High-throughput microscopy and robotic systems enable unbiased genomic screening of cellular processes. This powerful combination in yeast (Saccharomyces cerevisiae) advances understanding of complex cell biology.

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Area of Science:

  • Cell Biology
  • Genomics
  • Microscopy

Background:

  • High-throughput methodologies offer unbiased approaches to studying biological phenomena.
  • Automated cell manipulation and microscopy platforms facilitate genome-wide screening for genes impacting visualized cellular processes.

Purpose of the Study:

  • To describe the coupling of systematic genetic tools in Saccharomyces cerevisiae with robotic visualization systems.
  • To explore how this combination can address complex biological questions.

Main Methods:

  • Utilizing the budding yeast Saccharomyces cerevisiae as a model system.
  • Employing high-throughput microscopy screens.
  • Integrating systematic genetic tools with robotic visualization platforms.

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Competitive Genomic Screens of Barcoded Yeast Libraries
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Competitive Genomic Screens of Barcoded Yeast Libraries

Published on: August 11, 2011

Mating-based Overexpression Library Screening in Yeast
11:39

Mating-based Overexpression Library Screening in Yeast

Published on: July 6, 2018

Related Experiment Videos

Last Updated: May 29, 2026

High-throughput Yeast Plasmid Overexpression Screen
08:57

High-throughput Yeast Plasmid Overexpression Screen

Published on: July 27, 2011

Competitive Genomic Screens of Barcoded Yeast Libraries
11:59

Competitive Genomic Screens of Barcoded Yeast Libraries

Published on: August 11, 2011

Mating-based Overexpression Library Screening in Yeast
11:39

Mating-based Overexpression Library Screening in Yeast

Published on: July 6, 2018

Main Results:

  • The described methodologies enable unbiased, genome-wide screening of cellular functions.
  • This approach facilitates the study of complex and dynamic cellular structures and processes.

Conclusions:

  • The combination of high-throughput microscopy and yeast genetics provides a powerful approach to cell biology research.
  • This strategy is expected to generate new knowledge across all areas of cell biology.