The value of body surface potential maps in detecting abnormal ventricular wall motion

Area of Science:

• Cardiology
• Medical Imaging
• Electrophysiology

Background:

• Coronary artery disease (CAD) frequently leads to ventricular wall motion abnormalities.
• Body surface potential maps (BSPMs) offer a non-invasive method to assess cardiac electrical activity.
• Expanding the clinical utility of BSPMs in CAD requires understanding their relationship with mechanical function.

Purpose of the Study:

• To investigate the correlation between abnormal ventricular wall motion and BSPMs in patients with confirmed CAD.
• To evaluate the diagnostic performance of BSPMs in identifying specific coronary artery lesions based on wall motion abnormalities.

Main Methods:

• Analysis of BSPMs and left ventriculograms in 98 consecutive patients with angiographically proven CAD.
• Assessment of the timing of potential maximum and minimum during ventricular depolarization.
• Calculation of sensitivity, specificity, and predictive values for detecting LAD, LCX, RCA, and multi-vessel CAD.

Main Results:

• 50% of patients exhibited wall motion abnormalities on ventriculography.
• 56.1% of patients displayed abnormal "early reversal" in BSPMs during early ventricular depolarization (p < 0.001).
• Abnormal "early reversal" in BSPMs showed a strong association with abnormal ventricular wall motion.

Conclusions:

• Abnormal "early reversal" in BSPMs serves as a reliable indicator of abnormal ventricular wall motion in CAD.
• BSPMs demonstrate high sensitivity (85%) and specificity (80%) for detecting LAD lesions, including those with multi-vessel involvement.