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Published on: January 31, 2025
[Management of thyroid diseases during pregnancy]
Alicja Hubalewska-Dydejczyk1, Andrzej Lewiński, Andrzej Milewicz
1Department of Endocrinology, Jagiellonian University, Medical College, Krakow, Poland. alahub@cm-uj.krakow.pl
Managing thyroid dysfunction during pregnancy is crucial for maternal and fetal health. New Polish guidelines aim to standardize care, identify at-risk women, and establish trimester-specific hormone values for better outcomes.
Area of Science:
- Endocrinology
- Obstetrics and Gynecology
- Reproductive Medicine
Context:
- Thyroid dysfunction during pregnancy poses risks including subfertility, obstetrical complications, and adverse fetal development.
- Existing international guidelines provide a framework, but regional variations in ethnicity, socioeconomic status, and iodine intake necessitate localized recommendations.
- The 2007 Endocrine Society Practice Guideline aimed for uniformity but acknowledged areas of uncertainty and the need for population-specific adaptations.
Purpose:
- To develop comprehensive Polish guidelines for managing thyroid dysfunction in pregnant women.
- To identify women at risk for thyroid dysfunction requiring preconception, pregnancy, and postpartum endocrine care.
- To establish Polish trimester-specific reference ranges for thyroid hormones during pregnancy.
Summary:
- A Polish Task Force was established to create evidence-based guidelines for thyroid disorder management in pregnant women.
- Key objectives include targeted case finding, risk stratification, and defining trimester-specific thyroid hormone reference values.
- These guidelines aim to systematize and improve the endocrine care of pregnant women in Poland.
Impact:
- Standardize thyroid disorder management in pregnant women across Poland.
- Improve preconception, pregnancy, and postpartum care for women with thyroid dysfunction.
- Enhance fetal and maternal outcomes through optimized, localized endocrine care strategies.
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