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Updated: May 29, 2026
10:28
A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
Published on: June 26, 2020
Summary
Hepatitis A diagnoses in U.S. military members remained low from 2000-2010, significantly lower than pre-vaccine years. This decrease is attributed to widespread hepatitis A virus vaccination, though endemic country-born service members showed higher rates.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Hepatitis A virus (HAV) infection poses a risk to military personnel.
- Vaccination strategies aim to reduce infectious disease incidence in the armed forces.
Purpose of the Study:
- To determine the incidence of acute hepatitis A diagnoses in U.S. active component military members from 2000 to 2010.
- To compare these rates with historical data and identify risk factors.
Main Methods:
- Retrospective analysis of incident diagnoses of acute hepatitis A.
- Calculation of incidence rates per 100,000 person-years.
- Comparison of rates across different service member demographics.
Main Results:
- A total of 214 incident diagnoses of acute hepatitis A were recorded.
- The overall incidence rate was 1.37 per 100,000 person-years.
- Service members born in HAV-endemic countries had disproportionately higher diagnosis rates.
Conclusions:
- Widespread hepatitis A virus vaccination has successfully reduced overall incidence in the U.S. military.
- Targeted prevention strategies may be needed for service members from endemic regions.
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